Ipamorelin for Weight Loss: What to Know in 2024
IpamorelinĀ is a synthetic growth hormone secretagogue receptor agonist, which makes it like the natural peptide hormone ghrelin. As an analogue of ghrelin, ipamorelin is a potent stimulator of growth hormone secretion. It is also among the most selective of the ghrelin mimetics, which means ipamorelin has few unintended side effects. Ipamorelin has been studied for its ability to stimulate bone formation and as a potential treatment for post-operative ileus. It is also of interest in weight loss research for its ability to modify GH secretion, impact insulin release, and alter food intake.
Ipamorelin for Weight Loss
There has been a lot of research into using ipamorelin for weight loss, but this can be confusing given the fact that ghrelin, from which ipamorelin is derived, is often referred to as the hunger hormone. If a hormone stimulates appetite, how can it possibly be useful in weight loss? The answer to this question lies in how ipamorelin stimulates appetite and how the peptide alters energy balance to favor lean body mass as opposed to fat mass. The answer also lies in the intelligent use of ipamorelin which, when paired with proper diet and conditioning, can lead to profound fat burning.
Using ipamorelin for weight loss might be more accurately referred to as using ipamorelin for promoting leaning body mass. Ipamorelin is a potent growth hormone secretagogue. And growth hormone is known for stimulating growth, hence the name! Growth hormone (GH) does not simply stimulate growth in general, but rather stimulates the growth of lean body tissues like muscle and bone. It stimulates the burning of fat. So, increasing GH hormone levels helps to build muscle and bone density while reducing adipose (fat) tissue.
