Retatrutide - Ai-Peptides

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Retatrutide

GLP-3

Retatrutide is a GGG tri-agonist that targets GLP-1 and GIP receptors, akin to standard GLP-1 agonists, but also uniquely activates the glucagon receptor. Its actions on GLP-1 and GIP receptors promote delayed gastric emptying and appetite control, offering a comprehensive approach to obesity research distinct from older GLP-1 agonists. Further research is required.

Retatrutide is a next-generation tri-agonist—it engages three metabolic receptors at once: GLP-1, GIP, and glucagon. In simple terms, it’s designed to send multiple “metabolic signals” at the same time, which is why it’s drawing attention in obesity and metabolic research.

How is that different from older GLP-1–only tools? GLP-1 and GIP signaling are associated with appetite control and slower gastric emptying in research settings, while adding glucagon receptor activity introduces a complementary pathway often discussed around energy use and metabolic rate. This multi-pathway profile is what makes Retatrutide a distinctive subject of study. Further research is required; this is not an approved treatment.

What you get from AI Peptides is clean, verified material. Our Retatrutide is produced to a high research standard with ≥99% purity (typical), identity-confirmed by mass spectrometry, and purity-checked by HPLC. Each batch ships with a lot-specific Certificate of Analysis (COA) so you can see the actual test results—clear proof, not guesswork.

We keep specs consistent from batch to batch and track every lot number. That means you can reorder the profile you liked and expect the same analytical fingerprint—useful for comparative work, method development, and repeat experiments.

If you want a modern tri-agonist with transparent documentation and high purity, Retatrutide from AI Peptides delivers the essentials to move forward with confidence. For laboratory research only; not for human consumption or clinical/veterinary use.

$220 USD
1
$209 USD 5%
5
$198 USD 10%
10
$187 USD 15%
20+

$220 USD

Out of stock

Expiry date3/12/27
Date Produced3/12/25
CAS #2381089-83-2
FormulaC223H343F3N46O70
M.W.4731.33 g/mol
REF1002-RT
Purity99% HPLC
RUOResearch Use Only

Not for human or veterinary use. Made in USA

This product is intended as a research chemical only. Not for human use. Peptides will arrive in a lyophilized (powder) form for maximum stability.

Retatrutide is a new entrant into the rapidly-expanding space of anti-obesity peptides. It is known as a GGG tri-agonist. This means that Retatrutide works at all of the incretin receptors including GLP-1 and GIP as well as the glucagon receptor itself.

Sequence: YA1QGTFTSDYSIL2LDKK4AQA1AFIEYLLEGGPSSGAPPPS3
Molecular Formula: C223H343F3N46O70
Molecular Weight: 4731.33 g/mol
PubChem SID: 474492335
CAS Number: 2381089-83-2
Synonyms: LY-3437943, NOP2Y096GV

Storage Instructions:

All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.

Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you’re ready to reconstitute it with bacteriostatic water.

Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.

However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.

For further information on proper storage techniques, click the link below:

Peptide Storage Information

Certificate Of Analysis:

This product is intended as a research chemical only. Not for human use. Peptides will arrive in a lyophilized (powder) form for maximum stability.

Retatrutide is a new entrant into the rapidly-expanding space of anti-obesity peptides. It is known as a GGG tri-agonist. This means that Retatrutide works at all of the incretin receptors including GLP-1 and GIP as well as the glucagon receptor itself.

Sequence: YA1QGTFTSDYSIL2LDKK4AQA1AFIEYLLEGGPSSGAPPPS3
Molecular Formula: C223H343F3N46O70
Molecular Weight: 4731.33 g/mol
PubChem SID: 474492335
CAS Number: 2381089-83-2
Synonyms: LY-3437943, NOP2Y096GV

Storage Instructions:

All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.

Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you’re ready to reconstitute it with bacteriostatic water.

Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.

However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.

For further information on proper storage techniques, click the link below:

Peptide Storage Information

This product is intended as a research chemical only. Not for human use. Peptides will arrive in a lyophilized (powder) form for maximum stability.

Retatrutide is a new entrant into the rapidly-expanding space of anti-obesity peptides. It is known as a GGG tri-agonist. This means that Retatrutide works at all of the incretin receptors including GLP-1 and GIP as well as the glucagon receptor itself.

Sequence: YA1QGTFTSDYSIL2LDKK4AQA1AFIEYLLEGGPSSGAPPPS3
Molecular Formula: C223H343F3N46O70
Molecular Weight: 4731.33 g/mol
PubChem SID: 474492335
CAS Number: 2381089-83-2
Synonyms: LY-3437943, NOP2Y096GV

Storage Instructions:

All of our products are manufactured using the Lyophilization (Freeze Drying) process, which ensures that our products remain 100% stable for shipping for up to 3-4 months.
Once the peptides are reconstituted (mixed with bacteriostatic water), they must be stored in the fridge to maintain stability. After reconstitution, the peptides will remain stable for up to 30 days.

Lyophilization is a unique dehydration process, also known as cryodesiccation, where the peptides are frozen and then subjected to low pressure. This causes the water in the peptide vial to sublimate directly from solid to gas, leaving behind a stable, crystalline white structure known as lyophilized peptide. The puffy white powder can be stored at room temperature until you’re ready to reconstitute it with bacteriostatic water.

Once peptides have been received, it is imperative that they are kept cold and away from light. If the peptides will be used immediately, or in the next several days, weeks or months, short-term refrigeration under 4C (39F) is generally acceptable. Lyophilized peptides are usually stable at room temperatures for several weeks or more, so if they will be utilized within weeks or months such storage is typically adequate.

However, for longer term storage (several months to years) it is more preferable to store peptides in a freezer at -80C (-112F). When storing peptides for months or even years, freezing is optimal in order to preserve the peptide’s stability.

For further information on proper storage techniques, click the link below:

Peptide Storage Information

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Use our Peptide Reconstitution Calculator. Simply select your parameters to accurately calculate dosages.

1

mg =

100

mcg(µg)
Determines peptide concentration
Common Amounts: GLP-1s: 2–3mL, Peptides: 3mL

PEPTIDE DOSE

0.1 mg

DRAW SYRINGE TO

5 units

YOUR VIAL CONTAINS

10 doses

CONCENTRATION

2 mg/mL

Dose of Peptide

0.1 mg = 100 mcg(ÎĽg)

Peptide Strength

Bacteriostatic Water

Determines peptide concentration
Common Amounts: GLP-1s: 2mL to 3mL Peptides: 3mL

FAQ:

What is the purity of your peptides, and how can I verify their quality?

All Ai-Peptides products are manufactured in the USA under strict quality control. Each peptide is analyzed using HPLC and Mass Spectrometry to confirm identity and purity, typically ≥99%. Every batch comes with a Certificate of Analysis (COA) you can view to verify authenticity and research-grade quality.

Our peptides are shipped lyophilized (powder form) for maximum stability. Store them in a cool, dry place until use. For long-term preservation, keep them refrigerated or frozen. Once reconstituted with a suitable research-grade solvent, keep the solution cold and protected from light to maintain integrity.

All products on our website can be purchased in any quantity available, from a single vial to larger amounts, simply by adjusting the quantity in your cart. We do not currently offer special wholesale pricing or custom bulk arrangements.

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